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Country of origin : India
The C18 Analytical Column is a reverse-phase HPLC column commonly used in pharmaceutical QC and method development. Typical dimensions include 250mm length and 4.6mm internal diameter with 3–5 µm particle size options, providing a balance of resolution and backpressure for routine assays. Selection focuses on column dimensions, particle size, and phase bonding to meet assay throughput and resolution requirements. Procurement teams choose C18 columns to standardize analytical runs across QC laboratories and method transfer programs.
C18 bonded silica stationary phase supports a wide range of reverse-phase applications. Buyers evaluate pH range compatibility and endcapping options for method robustness. The column suits laboratories performing impurity profiling, assay quantitation, and stability-indicating methods where reproducible retention and separation efficiency are required.
C18 bonded silica columns provide strong hydrophobic interaction suitable for non-polar to moderately polar analytes in reverse-phase HPLC. Key technical selection factors include bonded phase density, endcapping status, particle size, and column dimensions that influence resolution and pressure. Analytical chemists prioritize these parameters to optimize selectivity and run time for method development and validation.
Use cases include pharmaceutical assay development, impurity profiling, and routine QC testing. The column is appropriate for method transfer between laboratories and for labs standardizing column inventories for consistent chromatographic performance. When requesting procurement details, specify required column dimensions, particle size, and expected run conditions so suppliers can match phase and packing specifications.
This product is part of our HPLC Components & Modules catalog for chromatographic procurement.
Request a C18 Analytical Column procurement quote. Provide column dimensions, particle-size preference, and required quantity to receive lead times and pricing. Include required performance test criteria if applicable.